- OBB
- Ocean Park Standoff
- Odd Mob
- Odd Mob & Pooks (feat. Hayley Trinca)
- Odd Mob & Poops
- Odella
- Oden & Fatzo
- Odesza
- Ofenbach
- Offaiah
- Offer Nissim
- Office Girls
- official
- Ola
- Olga Alex
- Olga Lounova
- Oliver Heldens
- Oliver Heldens & Shaun Frank
- Oliver Moldan
- Oliver Nelson
- Oliver Tree
- Olivia Holt
- Olivia Nelson
- Olivia Somerlyn
- Olly Alexander
- Olly Murs
- Omah Lay
- Omar Kamal
- Omar Veluz
- OMG Collective
- OMI
- One Bit
- One Direction
- OneRepublic
- Ono
- Ookay
- Oovermatic
- Orianthi
- Orion Starchild
- Orville Peck
- Oscar Loya
- OSH
- Oshri
- OT
- OT Quartet
- OTR
- Otto Orlandi
- Out Of Chaos
- Outasight
- Overplade
- Owen Paul
- Owen Westlake
- Owl City
- Owl City & Carly Rae Jepsen
- OWNBOSS
- Oxia
